SCHEMBL9202234

SCHEMBL9202234

Br[C](Br)C(Br)(Br)Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.41
TSHR P16473 1/20 0.41
CA5A P35218 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
CA4 P22748 1/20 0.38
NR1H2 P55055 1/20 0.37
BAX Q07812 1/20 0.37
ALDH1A1 P00352 1/20 0.36
RECQL P46063 1/20 0.36
SRC P12931 1/20 0.36
KCNA3 P22001 1/20 0.35
ALOX15 P16050 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465075 0.75 LTA4H (0.47) LTA4HTSHRCA5ACA5BCA4
SCHEMBL18644835 0.72 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
SCHEMBL16663875 0.72 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
SCHEMBL17386435 0.72 CA4 (0.42) LTA4HTSHRCA5ACA5BCA4
SCHEMBL7089314 0.71 LTA4H (0.50) LTA4HTSHRCA5ACA5BCA4
SCHEMBL6047052 0.70 CA4 (0.46) LTA4HTSHRCA4ALDH1A1RECQL
SCHEMBL10937511 0.70 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL10592534 0.70 CA4 (0.46) LTA4HTSHRCA5ACA5BCA4
SCHEMBL10503197 0.70 TSHR (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL6046974 0.70 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7114328-A None JP disclosed
JP-H07114328-A HEAT-RESISTANT HOLOGRAM FOR LAMINATED GLASS AND TRANSPARENT HEAT-INSULATING GLASS USING THE SAME NISSAN MOTOR CO LTD 1995-05-02 JP disclosed