Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | HRH2 | P25021 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181109 | 0.90 | HTT (0.44) | MEN1KMT2ANPSR1TMEM97SIGMAR1 | |
| SCHEMBL9184466 | 0.82 | MEN1 (0.46) | MEN1KMT2ANPSR1TMEM97SIGMAR1 | |
| SCHEMBL21906706 | 0.79 | MEN1 (0.47) | MEN1KMT2ANPSR1TMEM97SIGMAR1 | |
| SCHEMBL578446 | 0.78 | SMN1; SMN2 (0.54) | MEN1KMT2ANPSR1TMEM97SIGMAR1 | |
| SCHEMBL9177283 | 0.77 | MEN1 (0.43) | MEN1KMT2ANPSR1TMEM97SIGMAR1 | |
| SCHEMBL11258174 | 0.76 | KDM4C (0.46) | MEN1KMT2ANPSR1EP300CREBBP | |
| SCHEMBL2148636 | 0.76 | SMN1; SMN2 (0.49) | MEN1KMT2ANPSR1TMEM97SIGMAR1 | |
| SCHEMBL18740435 | 0.76 | MEN1 (0.50) | MEN1KMT2ANPSR1TMEM97SIGMAR1 | |
| SCHEMBL4184332 | 0.75 | KDM4C (0.47) | MEN1KMT2AEP300CREBBP | |
| SCHEMBL11175135 | 0.75 | MEN1 (0.45) | MEN1KMT2ASIGMAR1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413455-B1 | Azabicyclo quinolone carboxylic acids | PFIZER (US) | 1995-06-21 | — | — | EP | disclosed |
| EP-0413455-A2 | Azabicyclo quinolone carboxylic acids | PFIZER INC. (US) | 1991-02-20 | — | — | EP | disclosed |