Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.67 |
| ▸ | DRD3 | P35462 | 11/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 9/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206102 | 1.00 | DRD2 (0.67) | DRD2DRD3SIGMAR1HTR2AHTR1A | |
| SCHEMBL9199501 | 1.00 | DRD2 (0.67) | DRD2DRD3SIGMAR1HTR2AHTR1A | |
| SCHEMBL13630405 | 0.87 | DRD2 (0.57) | DRD2DRD3SIGMAR1HTR1AKDM4E | |
| SCHEMBL9202136 | 0.86 | DRD2 (0.67) | DRD2DRD3HTR2AHTR1AKDM4E | |
| SCHEMBL9202130 | 0.86 | DRD2 (0.67) | DRD2DRD3HTR2AHTR1AKDM4E | |
| SCHEMBL9205095 | 0.86 | DRD2 (0.67) | DRD2DRD3HTR2AHTR1AKDM4E | |
| SCHEMBL13629988 | 0.83 | DRD2 (0.58) | DRD2DRD3SIGMAR1HTR2AKDM4E | |
| SCHEMBL4482699 | 0.83 | DRD2 (0.58) | DRD2DRD3SIGMAR1HTR2AKDM4E | |
| SCHEMBL13630282 | 0.80 | DRD2 (0.55) | DRD2DRD3SIGMAR1HTR2AKDM4E | |
| SCHEMBL4489217 | 0.80 | DRD2 (0.55) | DRD2DRD3SIGMAR1HTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431580-B1 | Substituted cyclohexanols as central nervous system agents | WARNER LAMBERT CO (US) | 1995-03-08 | — | — | EP | claimed |