Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ESRRB | O95718 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202221 | 1.00 | MAPT (0.53) | MAPTSIGMAR1KCNH2TP53HPGD | |
| SCHEMBL9207165 | 1.00 | MAPT (0.53) | MAPTSIGMAR1KCNH2TP53HPGD | |
| SCHEMBL20968782 | 0.89 | MAPT (0.53) | MAPTSIGMAR1TP53HPGDTSHR | |
| SCHEMBL2351809 | 0.81 | TAAR1 (0.50) | MEN1KMT2AALDH1A1ALOX5 | |
| SCHEMBL25258805 | 0.81 | TSHR (0.43) | MAPTSIGMAR1KCNH2TP53HPGD | |
| SCHEMBL14524332 | 0.79 | ALOX5 (0.46) | MEN1KMT2AALOX5SLC6A2SLC6A4 | |
| SCHEMBL8804536 | 0.79 | TAAR1 (0.45) | MEN1KMT2AALDH1A1ALOX5SLC6A2 | |
| SCHEMBL19321713 | 0.79 | CYP1A2 (0.45) | MEN1KMT2ACYP1A2ALOX5SLC6A2 | |
| SCHEMBL8804326 | 0.79 | CYP1A2 (0.45) | MEN1KMT2ACYP1A2ALOX5SLC6A2 | |
| SCHEMBL2689350 | 0.77 | SLC6A4 (0.66) | MAPTSIGMAR1KCNH2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518110-B1 | Process for the preparation of pure enatiomers of 4-[4-(4'-tert.butylphenyl)-2-hydroxybutoxy]-benzoic acid and its alkyl ester | KLINGE CO CHEM PHARM FAB (DE) | 1995-08-09 | — | — | EP | claimed |
| US-5266721-A | Process for preparing the pure enantiomers of lifibrol and its alkyl esters | KLINGE PHARMA GMBH (DE) | 1993-11-30 | — | — | US | claimed |
| EP-0518110-A2 | Process for the preparation of pure enatiomers of 4-[4-(4'-tert.butylphenyl)-2-hydroxybutoxy]-benzoic acid and its alkyl ester | Klinge Pharma GmbH (DE) | 1992-12-16 | — | — | EP | claimed |
| JP-5155808-A | — | — | None | — | — | JP | disclosed |
| EP-0481253-B1 | p-Oxybenzoic acid derivatives, process for preparing them, and their use as medicaments | KLINGE CO CHEM PHARM FAB (DE) | 1994-12-28 | — | — | EP | disclosed |
| JP-H05155808-A | PRODUCTION OF PURE ENANTIOMER OF 4(4-(4'TERT-BUTYL PHENYL)-2HYDROXYBUTOXY) BENZOIC ACID AND ITS ALKYLESTER | KLINGE PHARM GMBH & CO | 1993-06-22 | — | — | JP | disclosed |
| US-5153353-A | Antilipemic agents | KLINGE PHARMA GMBH (DE) | 1992-10-06 | — | — | US | disclosed |
| EP-0481253-A2 | p-Oxybenzoic acid derivatives, process for preparing them, and their use as medicaments | Klinge Pharma GmbH (DE) | 1992-04-22 | — | — | EP | disclosed |
| EP-0133935-B1 | P-OXYBENZOIC ACID DERIVATIVES, METHODS FOR PREPARING THEM, AND THEIR USE FOR THE PREPARATION OF MEDICAMENTS WITH HYPOLIPEMIC ACTIVITY | Klinge Pharma GmbH (DE) | 1987-12-23 | — | — | EP | disclosed |
| US-4582857-A | ANTILIPEMIC AGENTS | KLINGE PHARMA GMBH (DE) | 1986-04-15 | — | — | US | disclosed |
| EP-0133935-A2 | p-oxybenzoic acid derivatives, methods for preparing them, and their use for the preparation of medicaments with hypolipemic activity | Klinge Pharma GmbH (DE) | 1985-03-13 | — | — | EP | disclosed |