SCHEMBL9203383

SCHEMBL9203383

CC1=C(CCc2ccc(Sc3ccc(CCC4=C(C)C(=O)NC4=O)cc3C3=C(C)C(=O)NC3=O)c(C3=C(C)C(=O)NC3=O)c2)C(=O)NC1=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3674394 0.76 DAO (0.36) MAOAMAOB
SCHEMBL3677368 0.74 XIAP (0.42) MAOAMAOB
SCHEMBL3678051 0.72 DAO (0.35) MAOAMAOB
SCHEMBL3677288 0.72 NR3C2 (0.36) MAOAMAOB
SCHEMBL9204436 0.70 STK10 (0.43)
SCHEMBL8443626 0.69 PTPN2 (0.35)
SCHEMBL27794707 0.69 MAOA (0.42) MAOAMAOB
SCHEMBL1133158 0.64 DAO (0.34)
SCHEMBL9203366 0.64 CDK4 (0.46)
SCHEMBL3672110 0.64 GSK3B (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0556203-B1 (POLY)SULFIDE CONTAINING POLYCITRACONIMIDES AND POLYITACONIMIDES AKZO NOBEL NV (NL) 1995-10-11 EP disclosed
US-5405918-A Accelerators for sulfur-vulcanization of rubber; tires AKZO NOBEL N.V. (NL) 1995-04-11 US disclosed
EP-0640114-A1 SULFUR-VULCANIZED RUBBER COMPOSITION Akzo Nobel N.V. (NL) 1995-03-01 EP disclosed
WO-1993023467-A1 SULFUR-VULCANIZED RUBBER COMPOSITION AKZO NOBEL N.V. (NL) 1993-11-25 WO disclosed