Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11986717 | 0.81 | F2 (0.63) | F2CYP11B1CYP11B2ESR1ESR2 | |
| SCHEMBL1260425 | 0.80 | CYP11B1 (0.66) | F2CYP11B1CYP11B2ESR1ESR2 | |
| SCHEMBL12939133 | 0.80 | F2 (0.61) | F2CYP11B1CYP11B2ESR1ESR2 | |
| SCHEMBL23989263 | 0.79 | ESR1 (0.66) | ESR1ESR2KDM4E | |
| SCHEMBL17348446 | 0.79 | AHR (0.57) | CHEK1SMN1; SMN2KDM4EHPGDNPC1 | |
| SCHEMBL5196023 | 0.78 | KDM4E (0.58) | SMN1; SMN2KDM4EHPGDALOX5MAOA | |
| SCHEMBL8856056 | 0.78 | ALOX5 (0.68) | F2KDM4EHPGDALOX5 | |
| SCHEMBL8235035 | 0.77 | F2 (0.58) | F2CYP11B1CYP11B2KIF11KDM4E | |
| SCHEMBL29090134 | 0.77 | F2 (0.58) | F2KDM4E | |
| SCHEMBL1460051 | 0.77 | F2 (0.58) | F2CYP11B1CYP11B2TLR9KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650599-A1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | OXIS INTERNATIONAL S.A. (FR) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994027155-A1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | BIOXYTECH (FR) | 1994-11-24 | — | — | WO | disclosed |