Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9215675 | 0.99 | TSHR (0.39) | TSHRNPSR1LMNATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9216303 | 0.99 | TSHR (0.39) | TSHRNPSR1LMNATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9212229 | 0.98 | TSHR (0.39) | TSHRNPSR1LMNATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9205111 | 0.96 | LMNA (0.39) | TSHRNPSR1LMNATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9203774 | 0.94 | LMNA (0.40) | TSHRNPSR1LMNATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9212494 | 0.84 | NPSR1 (0.53) | TSHRNPSR1TP53CYP2C9CYP1A2 | |
| Hydrochloric Acid SCHEMBL9208625 | 0.84 | NPSR1 (0.53) | TSHRNPSR1TP53CYP2C9CYP1A2 | |
| Hydrochloric Acid SCHEMBL9214108 | 0.83 | NPSR1 (0.51) | TSHRNPSR1CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL9168592 | 0.82 | TSHR (0.43) | TSHRNPSR1LMNATP53SMN1; SMN2 | |
| SCHEMBL9168598 | 0.82 | TSHR (0.43) | TSHRNPSR1LMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536169-B1 | [3H,7H]THIAZOLO [3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA (IT) | 1995-04-05 | — | — | EP | disclosed |
| EP-0536169-A1 | 3H,7H]THIAZOLO 3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT. | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-04-14 | — | — | EP | disclosed |
| WO-1991018906-A1 | [3H,7H]THIAZOLO[3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-12-12 | — | — | WO | disclosed |