Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453427 | 0.80 | CYP2D6 (0.46) | NPC1RAB9AHPGD | |
| SCHEMBL9528089 | 0.77 | CYP2D6 (0.41) | NPC1RAB9AHPGD | |
| SCHEMBL920737 | 0.75 | CYP11B1 (0.41) | FFAR1MAOBNAAA | |
| SCHEMBL3867576 | 0.73 | NR1I2 (0.46) | PLA2G4BDRD2DRD3MAOAPDE4D | |
| SCHEMBL921349 | 0.73 | CYSLTR2 (0.42) | FFAR1PLA2G4BMAOBNAAA | |
| SCHEMBL6208639 | 0.73 | L3MBTL1 (0.48) | RAB9AMAOAMAOB | |
| SCHEMBL921411 | 0.73 | IDO1 (0.44) | FFAR1DRD2DRD4DRD3 | |
| SCHEMBL4981505 | 0.73 | KCNA3 (0.73) | FFAR1PLA2G4BS1PR1DRD2DRD4 | |
| SCHEMBL920643 | 0.72 | FFAR1 (0.57) | FFAR1PLA2G4BS1PR1DRD2DRD4 | |
| SCHEMBL4982709 | 0.71 | KCNA3 (0.70) | FFAR1PLA2G4BS1PR1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |