Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.71 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | FRK | P42685 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.47 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206520 | 0.98 | PTGIR (0.73) | PTGIRPRKD3MAP4K4FRKMAPK9 | |
| SCHEMBL9208685 | 0.84 | PTGIR (0.69) | PTGIRMEN1CYP1A2KMT2ACYP2C9 | |
| SCHEMBL9206431 | 0.84 | PTGIR (0.69) | PTGIRMEN1CYP1A2KMT2ACYP2C9 | |
| SCHEMBL9208452 | 0.84 | PTGIR (0.69) | PTGIRMEN1CYP1A2KMT2ACYP2C9 | |
| SCHEMBL9206363 | 0.83 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10 | |
| SCHEMBL9206357 | 0.83 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10 | |
| SCHEMBL9198869 | 0.83 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10 | |
| SCHEMBL9202086 | 0.83 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10 | |
| SCHEMBL9200683 | 0.83 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10 | |
| Water SCHEMBL9203487 | 0.82 | PTGIR (0.97) | PTGIRKDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417449-B1 | Arylpyrazole derivatives as platelet aggregation inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5071866-A | Arylpyrazole derivatives as anti-platelet agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0417449-A1 | Arylpyrazole derivatives as platelet aggregation inhibitors | Bristol-Myers Squibb Company (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4994482-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-02-19 | — | — | US | disclosed |