Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CRHBP | P24387 | 3/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208452 | 1.00 | PTGIR (0.69) | PTGIRMEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL9206431 | 1.00 | PTGIR (0.69) | PTGIRMEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL9206520 | 0.85 | PTGIR (0.73) | PTGIRMEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL9203880 | 0.84 | PTGIR (0.71) | PTGIRMEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL9202086 | 0.82 | PTGIR (1.00) | PTGIRTSHRKDM4EHSD17B10 | |
| SCHEMBL9206363 | 0.82 | PTGIR (1.00) | PTGIRTSHRKDM4EHSD17B10 | |
| Water SCHEMBL9205391 | 0.82 | PTGIR (0.64) | PTGIRMEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL9206357 | 0.82 | PTGIR (1.00) | PTGIRTSHRKDM4EHSD17B10 | |
| SCHEMBL9206421 | 0.82 | PTGIR (0.64) | PTGIRMEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL9209473 | 0.82 | PTGIR (0.68) | PTGIRMEN1KMT2ACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417449-B1 | Arylpyrazole derivatives as platelet aggregation inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5071866-A | Arylpyrazole derivatives as anti-platelet agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0417449-A1 | Arylpyrazole derivatives as platelet aggregation inhibitors | Bristol-Myers Squibb Company (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4994482-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-02-19 | — | — | US | disclosed |