Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.48 |
| ▸ | RXRB | P28702 | 2/20 | 0.48 |
| ▸ | RXRG | P48443 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393208 | 0.88 | SLC7A5 (0.45) | RXRARXRBRXRGHPGDLMNA | |
| SCHEMBL644658 | 0.86 | SMPD1 (0.48) | RXRARXRBRXRGHPGDLMNA | |
| SCHEMBL9202219 | 0.85 | MRGPRX4 (0.51) | RXRARXRBRXRGHPGDLMNA | |
| SCHEMBL8305564 | 0.85 | PTGER1 (0.46) | RXRARXRBRXRGHPGDNPC1 | |
| SCHEMBL9393268 | 0.84 | MRGPRX4 (0.47) | RXRARXRBRXRGHPGDLMNA | |
| SCHEMBL9200286 | 0.83 | RXRA (0.46) | RXRARXRBRXRGHPGDLMNA | |
| SCHEMBL30102553 | 0.83 | HPGD (0.52) | RXRAHPGDLMNANPC1RAB9A | |
| SCHEMBL28903577 | 0.83 | HPGD (0.52) | RXRAHPGDLMNANPC1RAB9A | |
| SCHEMBL9200808 | 0.82 | SLC7A5 (0.43) | RXRARXRBRXRGHPGDLMNA | |
| SCHEMBL10253000 | 0.82 | SMPD1 (0.44) | RXRARXRBRXRGHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |