⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675211 | 0.75 | — | — | |
| SCHEMBL3060269 | 0.72 | MMP1 (0.48) | — | |
| SCHEMBL320068 | 0.72 | — | — | |
| SCHEMBL28293734 | 0.72 | MMP1 (0.48) | — | |
| Propyne SCHEMBL5761431 | 0.69 | — | — | |
| SCHEMBL27977830 | 0.69 | — | — | |
| SCHEMBL5909428 | 0.69 | MCL1 (0.55) | — | |
| SCHEMBL42050 | 0.69 | — | — | |
| SCHEMBL31852 | 0.69 | — | — | |
| SCHEMBL10011 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411664-B1 | 2-(2-Vinylpyrrolidinylthio)carbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1995-01-18 | — | — | EP | disclosed |
| US-5095013-A | Antibiotics | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |
| EP-0411664-A2 | 2-(2-Vinylpyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4735959-A | HYPOGLYCEMIC AGENTS | DR. KARL THOMAE GMBH (DE) | 1988-04-05 | — | — | US | disclosed |
| EP-0058779-B1 | CARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1984-09-19 | — | — | EP | disclosed |
| EP-0058779-A2 | Carboxamides, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1982-09-01 | — | — | EP | disclosed |