Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204539 | 1.00 | DPP4 (0.44) | DPP4CHRM2DRD1KDM4EHSD17B10 | |
| SCHEMBL9204536 | 1.00 | DPP4 (0.44) | DPP4CHRM2DRD1KDM4EHSD17B10 | |
| SCHEMBL9182588 | 0.90 | DPP4 (0.53) | DPP4CHRM2DRD1KDM4EHSD17B10 | |
| SCHEMBL9182597 | 0.90 | DPP4 (0.53) | DPP4CHRM2DRD1KDM4EHSD17B10 | |
| SCHEMBL9182591 | 0.90 | DPP4 (0.53) | DPP4CHRM2DRD1KDM4EHSD17B10 | |
| SCHEMBL10655952 | 0.83 | DPP4 (0.50) | DPP4CHRM2DRD1KDM4EHSD17B10 | |
| SCHEMBL10653563 | 0.83 | KMT2A (0.54) | DPP4CHRM2DRD1KDM4EHSD17B10 | |
| SCHEMBL10653881 | 0.82 | DPP4 (0.48) | DPP4CHRM2DRD1KDM4EHSD17B10 | |
| SCHEMBL30482921 | 0.81 | DPP4 (0.47) | DPP4CHRM2DRD1KDM4EHSD17B10 | |
| SCHEMBL2092020 | 0.81 | OPRK1 (0.40) | KDM4EHSD17B10LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413455-B1 | Azabicyclo quinolone carboxylic acids | PFIZER (US) | 1995-06-21 | — | — | EP | disclosed |
| US-5229396-A | Anti-bacterial azabicyclo quinolone carboxylic acids | PFIZER INC. (US) | 1993-07-20 | — | — | US | disclosed |
| US-5164402-A | Bactericides | PFIZER INC (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0413455-A2 | Azabicyclo quinolone carboxylic acids | PFIZER INC. (US) | 1991-02-20 | — | — | EP | disclosed |