Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 20/20 | 0.71 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.57 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.57 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203063 | 0.93 | AKR1B1 (0.71) | AKR1B1AKR1B10AKR1A1GLO1 | |
| SCHEMBL9870810 | 0.90 | AKR1B1 (0.67) | AKR1B1AKR1B10AKR1A1GLO1 | |
| SCHEMBL4560794 | 0.89 | AKR1B1 (0.69) | AKR1B1AKR1B10AKR1A1GLO1 | |
| SCHEMBL9870131 | 0.84 | AKR1B1 (0.67) | AKR1B1AKR1B10AKR1A1GLO1 | |
| SCHEMBL9871941 | 0.83 | AKR1B1 (1.00) | AKR1B1AKR1B10AKR1A1GLO1 | |
| SCHEMBL9209763 | 0.82 | AKR1B1 (0.57) | AKR1B1AKR1B10AKR1A1GLO1 | |
| SCHEMBL9374539 | 0.81 | AKR1B1 (0.79) | AKR1B1AKR1B10AKR1A1GLO1 | |
| SCHEMBL9870702 | 0.80 | AKR1B1 (0.54) | AKR1B1AKR1B10AKR1A1GLO1 | |
| SCHEMBL9204262 | 0.80 | AKR1B1 (1.00) | AKR1B1AKR1B10AKR1A1GLO1 | |
| SCHEMBL360713 | 0.77 | AKR1B1 (0.64) | AKR1B1AKR1B10AKR1A1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401981-B1 | Pyridazinone deriratives | PFIZER (US) | 1995-04-26 | — | — | EP | disclosed |