Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 2/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL579960 | 1.00 | CA1 (0.55) | CA1CA2TSHRKMT2ABIRC2 | |
| SCHEMBL14591439 | 0.91 | CA1 (0.52) | CA1CA2TSHRKMT2ABIRC2 | |
| SCHEMBL3237660 | 0.88 | KMT2A (0.48) | CA1CA2TSHRKMT2AMGAM | |
| Acetic Acid SCHEMBL28197363 | 0.87 | CA2 (0.44) | CA1CA2TSHRKMT2ABIRC2 | |
| Glutarate SCHEMBL6877091 | 0.87 | TSHR (0.55) | CA1CA2TSHRKMT2AHSD17B10 | |
| SCHEMBL17969530 | 0.87 | CA1 (0.52) | CA1CA2TSHRKMT2ABIRC2 | |
| Glutarate SCHEMBL28208949 | 0.84 | TSHR (0.52) | CA1CA2TSHRKMT2AHSD17B10 | |
| SCHEMBL10980193 | 0.84 | CA1 (0.42) | CA1CA2TSHRKMT2ABIRC2 | |
| SCHEMBL184812 | 0.83 | — | — | |
| SCHEMBL27817674 | 0.83 | CA1 (0.52) | CA1CA2TSHRKMT2ABIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643710-A1 | SYNTHESIS OF OPTICALLY ACTIVE LACTONES FROM L-ASPARTIC ACID AND INTERMEDIATES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5322942-A | Deprotecting and hydrolyzing protected aspartic acid diester, reacting with nitrosylating agent in presence of hydrogen halide, esterifying, reacting with acyl aryl derivative | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-06-21 | — | — | US | disclosed |
| WO-1992021675-A1 | SYNTHESIS OF OPTICALLY ACTIVE LACTONES FROM L-ASPARTIC ACID AND INTERMEDIATES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-12-10 | — | — | WO | disclosed |