SCHEMBL9205192

SCHEMBL9205192

CC1CCC(CC(C)(C)C)CC1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18799192 1.00 THRA (0.43) THRATHRBACHE
SCHEMBL7155825 0.87
SCHEMBL18660049 0.83 THRA (0.36) THRATHRB
SCHEMBL12898096 0.81 THRA (0.31) THRATHRB
SCHEMBL13202376 0.81 THRA (0.35) THRATHRB
SCHEMBL24113782 0.81 THRA (0.31) THRATHRB
SCHEMBL6712410 0.81 THRA (0.35) THRATHRB
SCHEMBL3000684 0.79 THRA (0.34) THRATHRB
SCHEMBL27048536 0.78
SCHEMBL16191111 0.78 CYP1A2 (0.33) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0421441-B1 Pantothenic acid derivatives FUJIREBIO KK (JP) 1995-01-25 EP disclosed
US-5120738-A Cardiovascular disorders FUJIREBIO INC. (JP) 1992-06-09 US disclosed
US-5032616-A Plants TRACOR, INC. 1991-07-16 US disclosed
EP-0421441-A2 Pantothenic acid derivatives FUJIREBIO INC. (JP) 1991-04-10 EP disclosed
EP-0258853-B1 4-SUBSTITUTED CYCLOHEXYLAMINE DERIVATIVES, FUNGICIDES CONTAINING THEM AND PROCESS FOR COMBATING FUNGI BASF Aktiengesellschaft (DE) 1990-07-11 EP disclosed
EP-0258853-A1 4-Substituted cyclohexylamine derivatives, fungicides containing them and process for combating fungi BASF Aktiengesellschaft (DE) 1988-03-09 EP disclosed