Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27519717 | 0.90 | KMT2A (0.65) | PTGS2CHRNA7MEN1KMT2AATM | |
| SCHEMBL9207390 | 0.89 | SMPD1 (0.52) | PTGS2PPP1CAMALT1CA9MAPK9 | |
| SCHEMBL9203678 | 0.86 | EPHX2 (0.48) | PTGS2CHRNA7PTGS1MALT1CA9 | |
| SCHEMBL9207613 | 0.86 | PTGS2 (0.44) | PTGS2CHRNA7PTGS1MALT1CA9 | |
| SCHEMBL9201370 | 0.85 | CHRNA7 (0.68) | PTGS2CHRNA7MEN1KMT2AATM | |
| SCHEMBL9201625 | 0.83 | PTGS2 (0.57) | PTGS2CHRNA7MEN1KMT2AATM | |
| SCHEMBL27400529 | 0.80 | AOC3 (0.47) | PTGS2CHRNA7MEN1KMT2AATM | |
| SCHEMBL9201499 | 0.80 | KMT2A (0.61) | PTGS2CHRNA7MEN1KMT2AATM | |
| SCHEMBL9202534 | 0.79 | PTGS2 (0.62) | PTGS2CHRNA7MEN1KMT2AATM | |
| SCHEMBL9209581 | 0.79 | MEN1 (0.60) | PTGS2CHRNA7MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418845-B1 | Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5134142-A | PYRAZOLE DERIVATIVES, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |
| EP-0418845-A1 | Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-27 | — | — | EP | disclosed |