SCHEMBL9205809

SCHEMBL9205809

CCC(N)c1ccc(Oc2c(F)c(F)c(F)c(F)c2F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.44
HSD17B10 Q99714 1/20 0.41
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
SLC2A1 P11166 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA13 Q8N1Q1 1/20 0.36
MAPT P10636 2/20 0.35
POLB P06746 1/20 0.35
HSP90AA1 P07900 1/20 0.35
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34
SCN4A P35499 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9525316 0.82 SLC6A4 (0.47) SLC6A4CYP1A2CYP2D6CYP2C19SLC2A1
SCHEMBL9216415 0.80 HSD17B10 (0.45) HSD17B10CYP1A2CYP2D6CYP2C19CA12
SCHEMBL12261552 0.77 LTA4H (0.52) SLC6A4SCN4ATSHR
SCHEMBL12497939 0.74 SLC6A4 (0.50) SLC6A4CYP1A2CYP2D6CYP2C19SLC2A1
SCHEMBL12498537 0.74 SLC6A4 (0.50) SLC6A4CYP1A2CYP2D6CYP2C19SLC2A1
SCHEMBL8285903 0.74 SLC6A4 (0.50) SLC6A4CYP1A2CYP2D6CYP2C19SLC2A1
SCHEMBL23092069 0.74 SLC6A4 (0.70) SLC6A4HSD17B10CYP1A2CYP2D6CYP2C19
SCHEMBL4859606 0.74 CYP1A2 (0.66) SLC6A4HSD17B10CYP1A2CYP2D6CYP2C19
SCHEMBL15157329 0.74 CYP1A2 (0.66) SLC6A4HSD17B10CYP1A2CYP2D6CYP2C19
SCHEMBL4963046 0.74 CYP1A2 (0.66) SLC6A4HSD17B10CYP1A2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0370704-B1 Aralkylamine derivatives, preparation thereof and fungicides containing the same UBE INDUSTRIES (JP) 1995-02-01 EP disclosed
US-5141941-A ARALKYLAMINE DERIVATIVES, AND FUNGICIDES CONTAINING THE SAME UBE INDUSTRIES, LTD. (JP) 1992-08-25 US disclosed
EP-0370704-A2 Aralkylamine derivatives, preparation thereof and fungicides containing the same UBE INDUSTRIES, LTD. (JP) 1990-05-30 EP disclosed