Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.35 |
| ▸ | FDPS | P14324 | 9/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205896 | 1.00 | TSHR (0.38) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL9204089 | 1.00 | TSHR (0.38) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL9210079 | 1.00 | TSHR (0.38) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL9210929 | 0.91 | TSHR (0.38) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL9214427 | 0.91 | TSHR (0.38) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL9211618 | 0.91 | TSHR (0.38) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL9207845 | 0.91 | TSHR (0.38) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL9211151 | 0.91 | TSHR (0.38) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL9210133 | 0.86 | TSHR (0.38) | TSHRTHRBGGPS1NAAAMEN1 | |
| SCHEMBL9211725 | 0.84 | FAAH (0.39) | LPAR1LPAR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |