SCHEMBL9206136

SCHEMBL9206136

CCCCCC(N)C(O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.55
AOC3 Q16853 7/20 0.53
ADRA2A P08913 1/20 0.50
ADRA2C P18825 1/20 0.50
LMNA P02545 1/20 0.50
HIF1A Q16665 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 2/20 0.48
ASAH1 Q13510 1/20 0.47
ACER2 Q5QJU3 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9207797 0.98 CSNK1E (0.58) CSNK1EAOC3ADRA2AADRA2CLMNA
SCHEMBL21278557 0.95 AOC3 (0.54) CSNK1EAOC3ADRA2AADRA2CLMNA
SCHEMBL8125880 0.95 AOC3 (0.54) CSNK1EAOC3ADRA2AADRA2CLMNA
SCHEMBL8135905 0.87 AOC3 (0.62) CSNK1EAOC3ADRA2AADRA2CLMNA
SCHEMBL851371 0.87 AOC3 (0.62) CSNK1EAOC3ADRA2AADRA2CLMNA
Hydrochloric Acid SCHEMBL3008842 0.85 AOC3 (0.61) CSNK1EAOC3ADRA2AADRA2CLMNA
SCHEMBL6267212 0.81 CSNK1E (0.54) CSNK1EAOC3ADRA2AADRA2CLMNA
SCHEMBL19391254 0.80 CSNK1E (0.57) CSNK1EAOC3LMNAKDM4EALDH1A1
Hydrochloric Acid SCHEMBL11126421 0.80 CSNK1E (0.49) CSNK1EAOC3
SCHEMBL11474474 0.80 CSNK1E (0.49) CSNK1EAOC3ADRA2AADRA2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0485069-B1 Process for producing optically active amines SUMITOMO CHEMICAL CO (JP) 1995-02-15 EP disclosed
US-5250546-A Administering as therapy for spastic paralysis; glutamic acid blocking agent; agricultural chemicals NIPPON CHEMIPHAR CO., LTD. (JP) 1993-10-05 US disclosed
US-5200561-A PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-04-06 US disclosed
US-5145998-A Reduction of oxime or silyloxime SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-09-08 US disclosed
EP-0237305-B1 A METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-06-03 EP disclosed
EP-0485069-A1 Process for producing optically active amines SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-05-13 EP disclosed
EP-0177245-B1 AMINO-ALCOHOL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION NIPPON CHEMIPHAR CO., LTD. (JP) 1991-04-10 EP disclosed
EP-0237305-A2 A method for producing optically active amines SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-16 EP disclosed
US-4644063-A MUSCLE RELAXANTS; AGRICULTURE NIPPON CHEMIPHAR CO., LTD. (JP) 1987-02-17 US disclosed