Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.49 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206136 | 0.98 | CSNK1E (0.55) | CSNK1EAOC3ALDH1A1ASAH1ACER2 | |
| SCHEMBL21278557 | 0.93 | AOC3 (0.54) | CSNK1EAOC3ALDH1A1ASAH1ACER2 | |
| SCHEMBL8125880 | 0.93 | AOC3 (0.54) | CSNK1EAOC3ALDH1A1ASAH1ACER2 | |
| SCHEMBL851371 | 0.85 | AOC3 (0.62) | CSNK1EAOC3ALDH1A1LMNAADRA2A | |
| SCHEMBL8135905 | 0.85 | AOC3 (0.62) | CSNK1EAOC3ALDH1A1LMNAADRA2A | |
| Hydrochloric Acid SCHEMBL3008842 | 0.84 | AOC3 (0.61) | CSNK1EAOC3ALDH1A1LMNAADRA2A | |
| SCHEMBL19391254 | 0.82 | CSNK1E (0.57) | CSNK1EAOC3ALDH1A1ASAH1ACER2 | |
| SCHEMBL10327288 | 0.82 | CSNK1E (0.57) | CSNK1EAOC3ALDH1A1ASAH1ACER2 | |
| SCHEMBL8001480 | 0.81 | SLC2A1 (0.49) | CSNK1EAOC3LMNAKDM4ESPHK1 | |
| Water SCHEMBL11439293 | 0.81 | CSNK1E (0.51) | CSNK1EALDH1A1LMNANAAASPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216999-B2 | Substituted pyrrolo[2,3-h][1,6]naphthyridines and compositions thereof as JAK inhibitors | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-12-22 | — | — | US | disclosed |
| EP-0485069-B1 | Process for producing optically active amines | SUMITOMO CHEMICAL CO (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-5250546-A | Administering as therapy for spastic paralysis; glutamic acid blocking agent; agricultural chemicals | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| US-5200561-A | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5145998-A | Reduction of oxime or silyloxime | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0237305-B1 | A METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-03 | — | — | EP | disclosed |
| EP-0485069-A1 | Process for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-05-13 | — | — | EP | disclosed |
| EP-0177245-B1 | AMINO-ALCOHOL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-04-10 | — | — | EP | disclosed |
| EP-0237305-A2 | A method for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-16 | — | — | EP | disclosed |