SCHEMBL92063

SCHEMBL92063

COc1ccccc1NC(=O)c1cc2ccccc2c(/N=N/c2ccc(S(=O)(=O)O)cc2)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.52
MEN1 O00255 6/20 0.52
KMT2A Q03164 6/20 0.52
POLB P06746 5/20 0.52
TDP1 Q9NUW8 2/20 0.52
USP2 O75604 1/20 0.52
NQO2 P16083 1/20 0.49
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ALDH1A1 P00352 5/20 0.46
TP53 P04637 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
GAA P10253 2/20 0.45
HTT P42858 1/20 0.45
MAOB P27338 1/20 0.45
NPC1 O15118 3/20 0.45
MPL P40238 1/20 0.45
CYP1A2 P05177 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14501388 0.90 ALDH1A1 (0.48) MAPTMEN1KMT2APOLBTDP1
SCHEMBL14565052 0.87 NQO2 (0.54) MAPTMEN1KMT2APOLBTDP1
SCHEMBL92075 0.87 KMT2A (0.56) MAPTMEN1KMT2APOLBTDP1
SCHEMBL10865544 0.87 NQO2 (0.51) MAPTMEN1KMT2APOLBTDP1
SCHEMBL31213814 0.87 NQO2 (0.58) MAPTMEN1KMT2APOLBTDP1
SCHEMBL31213822 0.86 NQO2 (0.60) MAPTMEN1KMT2APOLBTDP1
SCHEMBL11987797 0.86 NQO2 (0.60) MAPTMEN1KMT2APOLBTDP1
SCHEMBL29396852 0.86 NQO2 (0.60) MAPTMEN1KMT2APOLBTDP1
SCHEMBL14263638 0.84 KMT2A (0.55) MAPTMEN1KMT2APOLBTDP1
SCHEMBL14263561 0.84 NQO2 (0.64) MAPTMEN1KMT2APOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2146230-B1 Binary diketopyrrolopyrrole pigment compound for use in colour filters CLARIANT FINANCE BVI LTD (VG) 2012-09-12 EP disclosed
EP-2145926-B1 PR 254 pigment preparation for use in colour filters CLARIANT FINANCE BVI LTD (VG) 2012-05-30 EP disclosed
US-8128848-B2 Diketopyrrolopyrrole pigment composition for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2012-03-06 US disclosed
US-8128848-B2 Diketopyrrolopyrrole pigment composition for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2012-03-06 US disclosed
EP-2205682-B1 DIKETOPYRROLOPYRROLE PIGMENT COMPOSITION FOR USE IN COLOR FILTERS CLARIANT FINANCE BVI LTD (VG) 2011-03-09 EP disclosed
US-7892344-B2 P.R. 254 pigment preparation for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2011-02-22 US disclosed
US-7892344-B2 P.R. 254 pigment preparation for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2011-02-22 US disclosed
US-20100219384-A1 Diketopyrrolopyrrole Pigment Composition For Use In Color Filters CLARIANT FINANCE (BVI) LIMITED (VG) 2010-09-02 US disclosed
US-20100219384-A1 Diketopyrrolopyrrole Pigment Composition For Use In Color Filters CLARIANT FINANCE (BVI) LIMITED (VG) 2010-09-02 US disclosed
EP-2145926-A2 PR 254 pigment preparation for use in colour filters CLARIANT INTERNATIONAL LTD. (CH) 2010-01-20 EP disclosed
EP-2146230-A2 Binary diketopyrrolopyrrole pigment compound for use in colour filters CLARIANT INTERNATIONAL LTD. (CH) 2010-01-20 EP disclosed
US-20100006009-A1 P.R. 254 Pigment Preparation for use in Color Filters CLARIANT INTERNATIONAL LTD. (CH) 2010-01-14 US disclosed
US-20100006009-A1 P.R. 254 Pigment Preparation for use in Color Filters CLARIANT INTERNATIONAL LTD. (CH) 2010-01-14 US disclosed
WO-2009049736-A2 DIKETOPYRROLOPYRROLE PIGMENT COMPOSITION FOR USE IN COLOR FILTERS CLARIANT FINANCE (BVI) LIMITED (VG) 2009-04-23 WO disclosed