SCHEMBL9206495

SCHEMBL9206495

O=C(O)CNC(=O)CNC(=O)OCc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.43
EPHX1 P07099 2/20 0.40
ALDH1A1 P00352 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
PRSS1 P07477 1/20 0.38
TPSAB1 Q15661 1/20 0.38
TPSD1 Q9BZJ3 1/20 0.38
TPSG1 Q9NRR2 1/20 0.38
HTT P42858 1/20 0.36
DRD2 P14416 2/20 0.35
DRD4 P21917 2/20 0.35
DRD3 P35462 2/20 0.35
KDM1A O60341 1/20 0.35
RCOR1 Q9UKL0 1/20 0.35
CYP3A4 P08684 1/20 0.35
HTR7 P34969 1/20 0.34
HTR2B P41595 1/20 0.34
ENPP2 Q13822 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30898587 1.00 PNMT (0.43) PNMTEPHX1ALDH1A1NPC1RAB9A
SCHEMBL29430517 0.95 PNMT (0.47) PNMTEPHX1ALDH1A1NPC1RAB9A
SCHEMBL3459355 0.95 PNMT (0.47) PNMTEPHX1ALDH1A1NPC1RAB9A
Water SCHEMBL15362024 0.94 PNMT (0.46) PNMTEPHX1ALDH1A1NPC1RAB9A
SCHEMBL28324367 0.91 PNMT (0.41) PNMTEPHX1NPC1RAB9APRSS1
Glycine SCHEMBL25183413 0.91 PNMT (0.49) PNMTEPHX1ALDH1A1NPC1RAB9A
SCHEMBL8050275 0.86 PNMT (0.39) PNMTEPHX1ALDH1A1NPC1RAB9A
SCHEMBL5045467 0.85 HTT (0.43) PNMTEPHX1ALDH1A1NPC1RAB9A
SCHEMBL6030527 0.85 HTT (0.47) PNMTEPHX1ALDH1A1NPC1RAB9A
SCHEMBL29541016 0.85 HTT (0.47) PNMTEPHX1ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924669-A Carboxyl functionalized super-crosslinked polymer and preparation method and application thereof 中南民族大学 2024-04-26 CN claimed
EP-4714956-A2 IMPROVED METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE Daiichi Sankyo Company, Limited (JP) 2026-03-25 EP disclosed
US-12503489-B2 Method for producing antibody-drug conjugate DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-12-23 US disclosed
EP-3677589-B1 IMPROVED METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO CO LTD (JP) 2025-11-26 EP disclosed
US-20240376147-A1 METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-11-14 US disclosed
CN-117924669-A Carboxyl functionalized super-crosslinked polymer and preparation method and application thereof 中南民族大学 2024-04-26 CN disclosed
US-11945882-B2 Method for producing antibody-drug conjugate DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-04-02 US disclosed
US-20200385422-A1 METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2020-12-10 US disclosed
EP-3677589-A1 IMPROVED METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2020-07-08 EP disclosed
CN-111051330-A Improved preparation method of antibody-drug conjugate 第一三共株式会社 2020-04-21 CN disclosed
EP-0295316-B1 Antitumor amino acid and peptide derivatives of 1,4-bis[ (aminoalkyl and hydroxyaminoalkyl)- amino]-5,8 dihydroxyanthraquinones AMERICAN CYANAMID CO (US) 1995-11-08 EP disclosed
US-5130307-A Antibody inhibitors; treating organ graft rejection, fungal infections; antiinflammatory agents AMERICAN HOME PRODUCTS CORPORATION (US) 1992-07-14 US disclosed
EP-0489220-A1 Cytotoxic N,N'-bis (succinyl-peptide-) derivatives of 1,4-bis (aminoalkyl)-5,8-dihydroxyanthraquinones and antibody conjugates thereof AMERICAN CYANAMID COMPANY (US) 1992-06-10 EP disclosed
EP-0295316-A2 Antitumor amino acid and peptide derivatives of 1,4-bis[ (aminoalkyl and hydroxyaminoalkyl)- amino]-5,8 dihydroxyanthraquinones AMERICAN CYANAMID COMPANY (US) 1988-12-21 EP disclosed
US-4732970-A Antitumor amino acid and peptide derivatives of 1,4-bis(aminoalkyl and hydroxy-aminoalkyl)amino)-5,8-dihydroxyanthraquinones AMERICAN CYANAMID COMPANY (US) 1988-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200385422-A1 METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE UGT1A9, ALB, MRPL21 PNMT 3499/4885EPHX1 1623/4885ALDH1A1 257/4885
US-12503489-B2 Method for producing antibody-drug conjugate UGT1A9, ALB, MRPL21 PNMT 3499/4885EPHX1 1623/4885ALDH1A1 257/4885
US-20240376147-A1 METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE UGT1A9, ALB, MRPL21 PNMT 3499/4885EPHX1 1623/4885ALDH1A1 257/4885
US-11945882-B2 Method for producing antibody-drug conjugate UGT1A9, ALB, MRPL21 PNMT 3499/4885EPHX1 1623/4885ALDH1A1 257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.