Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870061 | 0.93 | AKR1B1 (0.77) | AKR1B1 | |
| SCHEMBL10431004 | 0.85 | AKR1B1 (0.57) | AKR1B1 | |
| SCHEMBL9203840 | 0.81 | AKR1B1 (0.56) | AKR1B1 | |
| SCHEMBL9209333 | 0.78 | KMT2A (0.58) | AKR1B1 | |
| SCHEMBL9870643 | 0.78 | AKR1B1 (0.52) | AKR1B1 | |
| SCHEMBL9870468 | 0.74 | AKR1B1 (0.50) | AKR1B1 | |
| SCHEMBL9202242 | 0.72 | AKR1B1 (0.79) | AKR1B1 | |
| SCHEMBL11192362 | 0.71 | AKR1B1 (0.58) | AKR1B1 | |
| SCHEMBL9204262 | 0.70 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL9209897 | 0.70 | AKR1B1 (0.85) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401981-B1 | Pyridazinone deriratives | PFIZER (US) | 1995-04-26 | — | — | EP | disclosed |
| US-4996204-A | Antidiabetic agents | PFIZER INC. (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0401981-A1 | Pyridazinone deriratives | PFIZER INC. (US) | 1990-12-12 | — | — | EP | disclosed |