SCHEMBL92067

SCHEMBL92067

COc1cc(Cl)c(OC)cc1N

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.83
NPC1 O15118 1/20 0.75
POLB P06746 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TAAR1 Q96RJ0 1/20 0.52
PKM P14618 2/20 0.48
ALDH1A1 P00352 6/20 0.46
CYP3A4 P08684 3/20 0.46
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HSP90AA1 P07900 3/20 0.44
MAPT P10636 2/20 0.44
MAPK1 P28482 1/20 0.44
RAB9A P51151 1/20 0.44
CCR6 P51684 1/20 0.44
CACNA1B Q00975 1/20 0.44
APBA1 Q02410 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466462 1.00 GAA (0.83) GAANPC1POLBL3MBTL1TAAR1
Hydrochloric Acid SCHEMBL5011472 0.98 GAA (0.79) GAANPC1POLBL3MBTL1TAAR1
SCHEMBL92047 0.91 GAA (1.00) GAANPC1POLBL3MBTL1TAAR1
SCHEMBL9416808 0.88 GAA (0.78) GAANPC1POLBL3MBTL1TAAR1
SCHEMBL5951825 0.88 GAA (0.78) GAANPC1POLBL3MBTL1TAAR1
SCHEMBL9293982 0.87 GAA (0.63) GAANPC1POLBL3MBTL1TAAR1
SCHEMBL4805724 0.86 GAA (0.75) GAANPC1POLBL3MBTL1PKM
SCHEMBL108063 0.86 NPC1 (1.00) GAANPC1POLBL3MBTL1TAAR1
Hydrochloric Acid SCHEMBL1401287 0.86 GAA (0.75) GAANPC1POLBL3MBTL1TAAR1
SCHEMBL9116148 0.86 NPC1 (0.83) GAANPC1POLBL3MBTL1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116003278-B Process for reducing agglomeration of 2, 5-dimethoxy-4-chloroacetanilide crystals 南通醋酸化工股份有限公司 2024-06-25 CN claimed
CN-116003278-A Process for reducing agglomeration of 2, 5-dimethoxy-4-chloroacetanilide crystals 南通醋酸化工股份有限公司 2023-04-25 CN claimed
CN-111285779-B Method for preparing 2,5-dimethoxy-4-chloroacetoacetanilide 南通醋酸化工股份有限公司 2023-03-28 CN claimed
CN-111116398-B Method for preparing naphthol AS-LC by micro-channel continuous method 泰安岳海新材料股份有限公司 2023-01-06 CN claimed
CN-110698353-B Preparation method of 4-chloro-2,5-dimethoxyaniline 河北彩客新材料科技股份有限公司 2022-11-22 CN claimed
CN-112079734-B Preparation method of 4-chloro-2, 5-dimethoxyaniline 常州大学 2022-03-18 CN claimed
CN-113307745-A Production method and system of naphthol AS series products 湖北浩元材料科技有限公司 2021-08-27 CN claimed
CN-112079734-A Preparation method of 4-chloro-2, 5-dimethoxyaniline 常州大学 2020-12-15 CN claimed
CN-111607247-A Mixed crystal type naphthol AS organic pigment and preparation method thereof 杭州百合科莱恩颜料有限公司 2020-09-01 CN claimed
CN-111285779-A Method for preparing high-quality 2, 5-dimethoxy-4-chloroacetoacetanilide 南通醋酸化工股份有限公司 2020-06-16 CN claimed
EP-0412121-A1 AZO PIGMENT COMPOSITION HAVING IMPROVED PROCESS HEAT STABILITY AND DRIED INK TRANSPARENCY. HOECHST CELANESE CORP (US) 1991-02-13 EP claimed
US-4968352-A Diaryl pigments with improved heat stability and transparency containing coupled mixed bis-diazotized diamines and acid-substituted aromatic amines HOECHST CELANESE CORPORATION (US) 1990-11-06 US claimed
WO-1989010385-A1 AZO PIGMENT COMPOSITION HAVING IMPROVED PROCESS HEAT STABILITY AND DRIED INK TRANSPARENCY HOECHST CELANESE CORPORATION (US) 1989-11-02 WO claimed
EP-0148022-A2 Silane quinacridone dyes, composite pigments obtainable therefrom, and processes for preparing the same Montedison S.p.A. (IT) 1985-07-10 EP claimed
EP-0140688-A2 Silane perylene dyes, composite pigments obtainable therefrom, and processes for preparing the same Montedison S.p.A. (IT) 1985-05-08 EP claimed
EP-0053713-B1 PROCESS FOR PREPARING 1-ACETYLAMINO-4-CHLORO-2,5 DIMETHOXYBENZENE HOECHST AKTIENGESELLSCHAFT (DE) 1984-07-04 EP claimed
US-4455424-A PIGMENTS AND DISPERSE DYES SANDOZ LTD. (CH) 1984-06-19 US claimed
EP-0053713-A1 Process for preparing 1-acetylamino-4-chloro-2,5 dimethoxybenzene HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-16 EP claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-4082803-A PROCESS FOR PREPARING 4-CHLORO-2,5-DIMETHOXY ANILINE HOECHST AKTIENGESELLSCHAFT (DT) 1978-04-04 US claimed