Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601238 | 1.00 | NPC1 (1.00) | NPC1GAAHSP90AA1HSP90AB1TAAR1 | |
| Hydrochloric Acid SCHEMBL3276689 | 0.98 | NPC1 (0.95) | NPC1GAAHSP90AA1HSP90AB1TAAR1 | |
| SCHEMBL9116148 | 0.91 | NPC1 (0.83) | NPC1GAAHSP90AA1HSP90AB1TAAR1 | |
| SCHEMBL5951825 | 0.88 | GAA (0.78) | NPC1GAAHSP90AA1HSP90AB1TAAR1 | |
| SCHEMBL1707866 | 0.88 | NPC1 (0.78) | NPC1GAATAAR1TUBB4ATUBB | |
| SCHEMBL4805724 | 0.86 | GAA (0.75) | NPC1GAATUBB4ATUBBTUBA3C | |
| SCHEMBL29466462 | 0.86 | GAA (0.83) | NPC1GAAHSP90AA1HSP90AB1TAAR1 | |
| SCHEMBL92067 | 0.86 | GAA (0.83) | NPC1GAAHSP90AA1HSP90AB1TAAR1 | |
| Hydrochloric Acid SCHEMBL1401287 | 0.86 | GAA (0.75) | NPC1GAAHSP90AA1HSP90AB1TAAR1 | |
| Hydrochloric Acid SCHEMBL5011472 | 0.84 | GAA (0.79) | NPC1GAAHSP90AA1HSP90AB1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118745133-A | Process for synthesizing dichloro amino aryl ether | 南京工业大学 | 2024-10-08 | — | — | CN | claimed |
| EP-4402132-A1 | FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING | Celloram, Inc. (US) | 2024-07-24 | — | — | EP | claimed |
| CN-118103357-A | FABP4/5 inhibitors, methods of use and methods of preparation | 塞洛拉姆股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| WO-2023043803-A1 | FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING | NOVIUS THERAPEUTICS, LLC (US) | 2023-03-23 | — | — | WO | claimed |
| CN-111116396-B | Preparation method of bosutinib raw material | 江苏远大仙乐药业有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-111116397-B | Synthesis method of bosutinib intermediate | 江苏远大仙乐药业有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-110204490-B | Preparation method of disubstituted 4-chloroquinoline-3-carbonitrile derivative and bosutinib | 新发药业有限公司 | 2021-01-01 | — | — | CN | claimed |
| CN-111116396-A | Preparation method of bosutinib raw material | 江苏远大仙乐药业有限公司 | 2020-05-08 | — | — | CN | claimed |
| CN-111116397-A | Synthesis method of bosutinib intermediate | 江苏远大仙乐药业有限公司 | 2020-05-08 | — | — | CN | claimed |
| WO-2019186429-A1 | A PROCESS FOR THE PREPARATION OF BOSUTINIB | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2019-10-03 | — | — | WO | claimed |
| CN-104876865-A | Preparation technology of bosutinib | NANJING LYNSCI CHEMICAL CO LTD | 2015-09-02 | — | — | CN | claimed |
| US-8288552-B2 | Dihydropyridone amidesas P2X7 modulators | ROCHE PALO ALTO LLC (US) | 2012-10-16 | — | — | US | claimed |
| US-4310623-A | THIO-PYRAZOLINE COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1982-01-12 | — | — | US | claimed |
| US-4288362-A | Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-08 | — | — | US | claimed |
| US-4264723-A | CONTAINING PYRAZOLONE COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1981-04-28 | — | — | US | claimed |
| US-20260132106-A1 | FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING | CELLORAM, INC. (US) | 2026-05-14 | — | — | US | disclosed |
| EP-3398939-B1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) | 2026-05-06 | — | — | EP | disclosed |
| EP-0008627-A2 | Quinazoline derivatives, azo dyes derived from the quinazolines and their use as pigments | BAYER AG (DE) | 1980-03-19 | — | — | EP | disclosed |
| US-4150019-A | COLORFAST, HEAT RESISTANT, MIGRATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-04-17 | — | — | US | disclosed |
| US-4014863-A | LACQUERS, PRINTING INKS, PAINTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132106-A1 | FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING | FABP5, FABP4, FABP1 | NPC1 206/4885GAA 4229/4885HSP90AA1 923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.