Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322047 | 0.89 | ELANE (0.54) | ELANEKDM1APPARGPPARACYP2C9 | |
| SCHEMBL4059798 | 0.85 | ELANE (0.72) | ELANEKDM1ANR1H2CA2LMNA | |
| SCHEMBL8323471 | 0.83 | ELANE (0.48) | ELANEKDM1APPARGPPARACYP2C9 | |
| SCHEMBL4060624 | 0.82 | ELANE (0.64) | ELANEKDM1ACYP2C9CYP2C19CA2 | |
| SCHEMBL23208392 | 0.81 | ELANE (0.51) | ELANEKDM1APPARGPPARACYP2C9 | |
| Trifluoromethanesulfonic Acid SCHEMBL7122599 | 0.80 | ELANE (0.45) | ELANEKDM1APPARGPPARACYP2C9 | |
| SCHEMBL919670 | 0.80 | ELANE (0.66) | ELANEKDM1ANR1H2CA2LMNA | |
| SCHEMBL978959 | 0.80 | ELANE (0.66) | ELANEKDM1ANR1H2CA2LMNA | |
| SCHEMBL4061370 | 0.80 | ELANE (0.81) | ELANEKDM1ACA2LMNAMAPT | |
| SCHEMBL12812870 | 0.78 | ELANE (0.51) | ELANEKDM1APPARGPPARACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871755-B2 | Photosensitive composition | KABUSHIKI KAISHA TOSHIBA (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090081582-A1 | irradiating a predetermined region of photosensitive layer, subjecting the photosensitive layer after baking to development treatment with an alkali aqueous solution to selectively remove the light-exposed part; has a photo-acid generator which generates an acid by the action of actinic radiation | KABUSHIKI KAISHA TOSHIBA | 2009-03-26 | — | — | US | disclosed |