Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9377480 | 0.93 | SIGMAR1 (0.54) | CYP1A2SIGMAR1POLBGAA | |
| Hydrochloric Acid SCHEMBL10451788 | 0.90 | SIGMAR1 (0.55) | CYP1A2SIGMAR1 | |
| SCHEMBL8878992 | 0.86 | CYP1A2 (0.46) | CYP1A2SIGMAR1POLBGAAKDM4E | |
| SCHEMBL28418301 | 0.81 | CYP1A2 (0.58) | CYP1A2SIGMAR1 | |
| SCHEMBL5320353 | 0.77 | CYP1A2 (0.54) | CYP1A2SIGMAR1ALDH1A1HPGD | |
| SCHEMBL26136877 | 0.77 | CYP1A2 (0.54) | CYP1A2SIGMAR1 | |
| SCHEMBL9206919 | 0.77 | CYP1A2 (0.54) | CYP1A2SIGMAR1 | |
| SCHEMBL11697439 | 0.76 | CYP1A2 (0.52) | CYP1A2SIGMAR1MEN1ALDH1A1LMNA | |
| SCHEMBL20220221 | 0.74 | CYP1A2 (0.50) | CYP1A2SIGMAR1 | |
| SCHEMBL472224 | 0.74 | CYP1A2 (0.56) | CYP1A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |