Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 16/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186631 | 0.88 | PTPN1 (0.59) | PTPN1ABCG2CAPN1KDM4ELMNA | |
| SCHEMBL9198648 | 0.86 | MAPT (0.45) | PTPN1ABCG2CAPN1DPP4KDM4E | |
| SCHEMBL7186606 | 0.86 | PTPN1 (0.51) | PTPN1DPP4LMNAMAPTATM | |
| SCHEMBL7186226 | 0.85 | PTPN1 (0.53) | PTPN1 | |
| SCHEMBL7188905 | 0.85 | PTPN1 (0.51) | PTPN1ABCG2CAPN1 | |
| SCHEMBL7186221 | 0.85 | PTPN1 (0.53) | PTPN1 | |
| SCHEMBL7185914 | 0.85 | PTPN1 (0.46) | PTPN1DPP4MAPT | |
| SCHEMBL9275370 | 0.85 | PTPN1 (0.49) | PTPN1ABCG2CAPN1 | |
| SCHEMBL9197571 | 0.84 | PTPN1 (0.47) | PTPN1ABCG2DPP4MAPT | |
| SCHEMBL9276155 | 0.84 | PTPN1 (0.44) | PTPN1DPP4LMNAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |