Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275370 | 0.92 | PTPN1 (0.49) | PTPN1 | |
| SCHEMBL7184863 | 0.91 | LMNA (0.47) | LMNASMN1; SMN2MAPTALDH1A1ATM | |
| SCHEMBL7186606 | 0.91 | PTPN1 (0.51) | PTPN1LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9274284 | 0.87 | PTPN1 (0.35) | PTPN1LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7192285 | 0.84 | CYP1A1 (0.48) | PTPN1LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9206940 | 0.84 | PTPN1 (0.46) | PTPN1LMNASMN1; SMN2MAPTATM | |
| SCHEMBL7185914 | 0.84 | PTPN1 (0.46) | PTPN1MAPTCYP1A1CYP1B1DPP4 | |
| SCHEMBL9197571 | 0.83 | PTPN1 (0.47) | PTPN1MAPTDPP4 | |
| SCHEMBL7179943 | 0.83 | PTPN1 (0.46) | PTPN1LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7179055 | 0.83 | LMNA (0.49) | PTPN1LMNASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |