Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202545 | 0.89 | CA1 (0.47) | CA1CA12CA9KMT2AMEN1 | |
| SCHEMBL9204225 | 0.87 | CA12 (0.51) | CA1CA12CA9KMT2AMEN1 | |
| SCHEMBL9199959 | 0.85 | CA1 (0.47) | CA1CA12CA9KMT2AMEN1 | |
| SCHEMBL9530329 | 0.84 | CA12 (0.47) | CA1CA12CA9KMT2AMEN1 | |
| SCHEMBL9207067 | 0.83 | NQO1 (0.49) | CA1CA12CA9KMT2AMEN1 | |
| SCHEMBL9203395 | 0.83 | KMT2A (0.47) | CA1CA12CA9KMT2AMEN1 | |
| SCHEMBL7615388 | 0.81 | CA1 (0.48) | CA1CA12CA9KMT2AMEN1 | |
| SCHEMBL9201369 | 0.81 | CA12 (0.47) | CA1CA12CA9KMT2AMEN1 | |
| SCHEMBL9199710 | 0.80 | F12 (0.46) | CA1CA12CA9KMT2AMEN1 | |
| SCHEMBL7617421 | 0.80 | MEN1 (0.51) | CA1CA12CA9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550493-B1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | UPJOHN CO (US) | 1995-08-09 | — | — | EP | claimed |