Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204225 | 0.90 | CA12 (0.51) | CA12CA9KMT2AMEN1ALDH1A1 | |
| SCHEMBL9203395 | 0.85 | KMT2A (0.47) | CA12CA9KMT2AMEN1ALDH1A1 | |
| SCHEMBL9201369 | 0.85 | CA12 (0.47) | CA12CA9POLBKMT2AMEN1 | |
| SCHEMBL9202545 | 0.84 | CA1 (0.47) | CA12CA9KMT2ANPSR1MEN1 | |
| SCHEMBL9207152 | 0.84 | CA1 (0.45) | CA12CA9POLBKMT2AMEN1 | |
| SCHEMBL9528732 | 0.83 | CA12 (0.45) | CA12CA9KMT2AMEN1ALDH1A1 | |
| SCHEMBL9199959 | 0.81 | CA1 (0.47) | CA12CA9KMT2AMEN1ALDH1A1 | |
| SCHEMBL9207067 | 0.81 | NQO1 (0.49) | CA12CA9POLBKMT2AMEN1 | |
| SCHEMBL9199710 | 0.78 | F12 (0.46) | CA12CA9KMT2ANPSR1MEN1 | |
| SCHEMBL7617421 | 0.78 | MEN1 (0.51) | CA12CA9POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550493-A1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1993-07-14 | — | — | EP | claimed |
| WO-1992006083-A1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-04-16 | — | — | WO | claimed |