Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208153 | 0.92 | NPC1 (0.64) | NPC1RAB9AHTTMEN1KMT2A | |
| SCHEMBL9205672 | 0.87 | RAB9A (0.53) | NPC1RAB9AHTTMEN1KMT2A | |
| SCHEMBL9208422 | 0.87 | MEN1 (0.46) | NPC1RAB9AHTTMEN1KMT2A | |
| SCHEMBL7608938 | 0.86 | KMT2A (0.45) | NPC1RAB9AHTTMEN1KMT2A | |
| SCHEMBL9200971 | 0.86 | MEN1 (0.43) | NPC1RAB9AHTTMEN1KMT2A | |
| SCHEMBL7616921 | 0.86 | MEN1 (0.57) | NPC1RAB9AHTTMEN1KMT2A | |
| SCHEMBL7640498 | 0.82 | CA12 (0.51) | NPC1RAB9AHTTMEN1KMT2A | |
| SCHEMBL9202732 | 0.82 | CA12 (0.51) | NPC1RAB9AHTTMEN1KMT2A | |
| SCHEMBL9208681 | 0.81 | CA12 (0.50) | NPC1RAB9AHTTMEN1KMT2A | |
| SCHEMBL9205774 | 0.81 | RAB9A (0.53) | NPC1RAB9AMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550493-B1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | UPJOHN CO (US) | 1995-08-09 | — | — | EP | claimed |