SCHEMBL9207458

SCHEMBL9207458

CCOCCN(C(=O)CCl)c1c(CC)cccc1CC

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.84
TDP1 Q9NUW8 2/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
TP53 P04637 6/20 0.65
ALDH1A1 P00352 6/20 0.63
CYP3A4 P08684 1/20 0.63
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
PAX8 Q06710 3/20 0.40
JAK2 O60674 1/20 0.40
GPX4 P36969 1/20 0.39
KDM4E B2RXH2 2/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
POLB P06746 2/20 0.36
THRB P10828 1/20 0.36
GLA P06280 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27474836 0.93 NR1I2 (0.74) NR1I2TDP1MEN1KMT2ATP53
SCHEMBL9212304 0.92 TP53 (0.76) NR1I2TDP1MEN1KMT2ATP53
Pretilachlor SCHEMBL7932522 0.92 NR1I2 (1.00) NR1I2TDP1MEN1KMT2ATP53
Pretilachlor SCHEMBL63720 0.92 NR1I2 (1.00) NR1I2TDP1MEN1KMT2ATP53
Pretilachlor SCHEMBL27361223 0.90 NR1I2 (0.97) NR1I2TDP1MEN1KMT2ATP53
Pretilachlor SCHEMBL28820473 0.90 NR1I2 (0.97) NR1I2TDP1MEN1KMT2ATP53
SCHEMBL11233629 0.90 NR1I2 (0.69) NR1I2TDP1MEN1KMT2ATP53
SCHEMBL8734929 0.89 NR1I2 (0.85) NR1I2TDP1MEN1KMT2ATP53
SCHEMBL6907864 0.88 NR1I2 (0.75) NR1I2TDP1MEN1KMT2ATP53
SCHEMBL11035094 0.86 NR1I2 (0.71) NR1I2TDP1MEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0365484-B1 SULFAMOYL PHENYL UREAS CIBA-GEIGY AG (CH) 1993-01-07 EP claimed
EP-0281521-B1 HERBICIDAL COMPOSITIONS CIBA-GEIGY AG (CH) 1992-07-08 EP claimed
US-5108482-A Protect crep plant against phytotoxic action of herbicide; plant growth regulator CIBA-GEIGY CORPORATION (US) 1992-04-28 US claimed
EP-0397602-A1 N-phenylpyrrolidines CIBA-GEIGY AG (CH) 1990-11-14 EP claimed
EP-0357557-A2 Synergistic mixture CIBA-GEIGY AG (CH) 1990-03-07 EP claimed
EP-0281521-A2 Herbicidal compositions CIBA-GEIGY AG (CH) 1988-09-07 EP claimed
EP-0378508-B1 Antidotes to modify the resistance of cultivated plants to agrochemical agents CIBA GEIGY AG (CH) 1995-03-01 EP disclosed
US-5215570-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed
US-5175289-A Antidotes for protecting cultivated plants from the phytotoxic action of herbicides CIBA-GEIGY CORPORATION (US) 1992-12-29 US disclosed
EP-0281521-B1 HERBICIDAL COMPOSITIONS CIBA-GEIGY AG (CH) 1992-07-08 EP disclosed
US-5108482-A Protect crep plant against phytotoxic action of herbicide; plant growth regulator CIBA-GEIGY CORPORATION (US) 1992-04-28 US disclosed
US-5041663-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed
US-5041157-A Protecting soybeans or cereals CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed
US-4618361-A COUNTER-AGENT OR SAFENER CIBA-GEIGY CORPORATION (US) 1986-10-21 US disclosed
US-4601745-A Composition for the protection of cultivated plants against the phytotoxic action of herbicides CIBA-GEIGY CORPORATION (US) 1986-07-22 US disclosed
US-4579691-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-04-01 US disclosed
US-4576628-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-03-18 US disclosed
US-4566901-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-01-28 US disclosed
US-4530716-A Plant safening agent CIBA-GEIGY CORPORATION (US) 1985-07-23 US disclosed
US-4523947-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1985-06-18 US disclosed