SCHEMBL6907864

SCHEMBL6907864

CCc1cccc(CC)c1N(CCOC)C(=O)CCl

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.75
TP53 P04637 5/20 0.74
KMT2A Q03164 3/20 0.61
TDP1 Q9NUW8 2/20 0.61
MEN1 O00255 2/20 0.61
ALDH1A1 P00352 3/20 0.56
CYP3A4 P08684 1/20 0.56
KDM4E B2RXH2 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
PAX8 Q06710 2/20 0.40
JAK2 O60674 1/20 0.40
THRB P10828 1/20 0.40
GPX4 P36969 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TRPA1 O75762 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9210625 0.92 TP53 (0.68) NR1I2TP53KMT2ATDP1MEN1
SCHEMBL9207458 0.88 NR1I2 (0.84) NR1I2TP53KMT2ATDP1MEN1
Pretilachlor SCHEMBL63720 0.86 NR1I2 (1.00) NR1I2TP53KMT2ATDP1MEN1
Pretilachlor SCHEMBL7932522 0.86 NR1I2 (1.00) NR1I2TP53KMT2ATDP1MEN1
SCHEMBL10736930 0.85 NR1I2 (0.57) NR1I2TP53KMT2ATDP1MEN1
Alachlor SCHEMBL15501 0.85 TP53 (1.00) NR1I2TP53KMT2ATDP1MEN1
Alachlor SCHEMBL3955304 0.85 TP53 (1.00) NR1I2TP53KMT2ATDP1MEN1
Pretilachlor SCHEMBL28820473 0.85 NR1I2 (0.97) NR1I2TP53KMT2ATDP1MEN1
Pretilachlor SCHEMBL27361223 0.85 NR1I2 (0.97) NR1I2TP53KMT2ATDP1MEN1
Acetochlor SCHEMBL18115344 0.84 TP53 (0.80) NR1I2TP53KMT2ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5912208-A NONIONIC SURFACTANTS OF GLYCEROL-BASED POLYETHER HAVING A POTENTIATING EFFECT ON BACTERICIDES, INSECTICIDES, MITICIDES, HERBICIDES AND PLANT GROWTH REGULATORS; NO CHEMICAL DAMAGE WHEN A MIXTURE IS APPLIED TO CROPS KAO CORPORATION (JP) 1999-06-15 US claimed
EP-0365484-B1 SULFAMOYL PHENYL UREAS CIBA-GEIGY AG (CH) 1993-01-07 EP claimed
EP-0281521-B1 HERBICIDAL COMPOSITIONS CIBA-GEIGY AG (CH) 1992-07-08 EP claimed
US-5108482-A Protect crep plant against phytotoxic action of herbicide; plant growth regulator CIBA-GEIGY CORPORATION (US) 1992-04-28 US claimed
EP-0397602-A1 N-phenylpyrrolidines CIBA-GEIGY AG (CH) 1990-11-14 EP claimed
EP-0357557-A2 Synergistic mixture CIBA-GEIGY AG (CH) 1990-03-07 EP claimed
EP-0281521-A2 Herbicidal compositions CIBA-GEIGY AG (CH) 1988-09-07 EP claimed
US-20240147997-A1 Herbicidal Compositions NUTRIEN AG SOLUTIONS (CANADA) INC (CA) 2024-05-09 US disclosed
US-11910795-B2 Natural indole auxin and aminopolycarboxylic acid herbicidal compositions SUNCOR ENERGY INC. (CA) 2024-02-27 US disclosed
US-20220046920-A1 Herbicidal Compositions NUTRIEN AG SOLUTIONS (CANADA) INC (CA) 2022-02-17 US disclosed
US-6706666-B2 MIXTURE OF AN ORGANONITROGEN COMPOUND AND CHELATE COMPOUND KAO CORPORATION (JP) 2004-03-16 US disclosed
EP-0702897-B1 Method for enhancing the efficacy of agricultural chemicals, adjuvant composition for agricultural chemicals and agricultural chemical composition KAO CORP (JP) 2003-04-02 EP disclosed
US-20010029240-A1 ENHANCER COMPOSITION FOR AGRICULTURAL CHEMICALS AND AGRICULTURAL CHEMICAL COMPOSITION HASEBE KEIKO (JP) 2001-10-11 US disclosed
US-4576628-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-03-18 US disclosed
US-4566901-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-01-28 US disclosed
US-4530716-A Plant safening agent CIBA-GEIGY CORPORATION (US) 1985-07-23 US disclosed
US-4523947-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1985-06-18 US disclosed
US-4493726-A PLANT SAFENING AGENT CIBA GEIGY CORPORATION (US) 1985-01-15 US disclosed
WO-1983002906-A1 ENCAPSULATION BY ENTRAPMENT WITHIN POLYHYDROXY POLYMER BORATES US AGRICULTURE (US) 1983-09-01 WO disclosed
EP-0055693-A1 Use of phenyl pyrimidines as protecting agents for culture plants against phytotoxic damage caused by herbicides CIBA-GEIGY AG (CH) 1982-07-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220046920-A1 Herbicidal Compositions DDT, IDO1, IDO2 NR1I2 3556/4885TP53 1495/4885KMT2A 1250/4885
US-11910795-B2 Natural indole auxin and aminopolycarboxylic acid herbicidal compositions DDC, AADAT, IDO1 NR1I2 4044/4885TP53 1166/4885KMT2A 810/4885
US-20240147997-A1 Herbicidal Compositions DDT, IDO1, IDO2 NR1I2 3556/4885TP53 1495/4885KMT2A 1250/4885
US-20010029240-A1 ENHANCER COMPOSITION FOR AGRICULTURAL CHEMICALS AND AGRICULTURAL CHEMICAL COMPOSITION MYB, PHOSPHO1, AS3MT NR1I2 1973/4885TP53 2495/4885KMT2A 148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.