Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127415 | 0.74 | TSHR (0.46) | MAPTPOLBTSHRGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9205600 | 0.69 | MAPT (0.39) | MAPTTSHRBRD4CREBBPALDH1A1 | |
| Diethyl Phthalate SCHEMBL27742347 | 0.66 | TSHR (0.95) | MAPTTSHRALDH1A1L3MBTL1MAPK1 | |
| Diethyl Phthalate SCHEMBL19252611 | 0.66 | TSHR (0.95) | TSHRALDH1A1L3MBTL1MAPK1HSD17B10 | |
| Diethyl Phthalate SCHEMBL7520316 | 0.66 | TSHR (0.95) | MAPTTSHRALDH1A1L3MBTL1MAPK1 | |
| Diethyl Phthalate SCHEMBL28775845 | 0.66 | TSHR (0.95) | TSHRALDH1A1L3MBTL1MAPK1HSD17B10 | |
| SCHEMBL16752384 | 0.65 | TSHR (0.65) | MAPTPOLBTSHRALDH1A1L3MBTL1 | |
| Diethyl Phthalate SCHEMBL28168029 | 0.65 | TSHR (0.91) | TSHRALDH1A1L3MBTL1MAPK1HSD17B10 | |
| Diethyl Phthalate SCHEMBL22296 | 0.64 | TSHR (1.00) | MAPTTSHRALDH1A1L3MBTL1MAPK1 | |
| Diethyl Phthalate SCHEMBL29404255 | 0.64 | TSHR (1.00) | MAPTTSHRALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385271-B1 | Tetrahydroquinolines and method of preparation | EASTMAN KODAK CO (US) | 1995-10-25 | — | — | EP | disclosed |
| EP-0385271-A1 | Tetrahydroquinolines and method of preparation | EASTMAN KODAK COMPANY (US) | 1990-09-05 | — | — | EP | disclosed |