Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203879 | 0.93 | NQO1 (0.49) | P2RX1RAB9ANPC1MAOBMAOA | |
| SCHEMBL9200984 | 0.93 | MAOB (0.48) | P2RX1RAB9ANPC1MAOBMAOA | |
| SCHEMBL9202075 | 0.90 | NQO1 (0.53) | RAB9ANPC1MAOBMAOACTDSP1 | |
| SCHEMBL9199959 | 0.88 | CA1 (0.47) | P2RX1RAB9ANPC1MAOBMEN1 | |
| SCHEMBL8441905 | 0.87 | P2RX1 (0.54) | P2RX1RAB9ANPC1MAOBMEN1 | |
| SCHEMBL9201369 | 0.86 | CA12 (0.47) | RAB9ANPC1MAOBMAOACTDSP1 | |
| SCHEMBL9206802 | 0.85 | KCNQ3 (0.50) | NT5E | |
| SCHEMBL7617329 | 0.84 | MAOB (0.48) | RAB9ANPC1MAOBMAOAMEN1 | |
| SCHEMBL9207126 | 0.84 | MAOB (0.47) | P2RX1RAB9ANPC1MAOBMAOA | |
| SCHEMBL9207067 | 0.83 | NQO1 (0.49) | RAB9ANPC1MAOBMAOACTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550493-B1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | UPJOHN CO (US) | 1995-08-09 | — | — | EP | claimed |
| EP-0550493-A1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1993-07-14 | — | — | EP | claimed |
| WO-1992006083-A1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-04-16 | — | — | WO | claimed |
| EP-0550493-B1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | UPJOHN CO (US) | 1995-08-09 | — | — | EP | disclosed |