Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 18/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 18/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 14/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 14/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200984 | 0.87 | MAOB (0.48) | NT5E | |
| SCHEMBL9208790 | 0.86 | KCNQ3 (0.56) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL9202301 | 0.86 | KMT2A (0.51) | — | |
| SCHEMBL9202749 | 0.86 | KCNQ3 (0.52) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL9208185 | 0.85 | P2RX1 (0.51) | NT5E | |
| SCHEMBL9199959 | 0.83 | CA1 (0.47) | NT5E | |
| SCHEMBL9202276 | 0.82 | ALDH1A1 (0.54) | — | |
| SCHEMBL9203879 | 0.81 | NQO1 (0.49) | NT5E | |
| SCHEMBL8441905 | 0.80 | P2RX1 (0.54) | NT5E | |
| SCHEMBL7617329 | 0.79 | MAOB (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550493-B1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | UPJOHN CO (US) | 1995-08-09 | — | — | EP | claimed |
| EP-0550493-A1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1993-07-14 | — | — | EP | claimed |
| WO-1992006083-A1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-04-16 | — | — | WO | claimed |