SCHEMBL9208454

SCHEMBL9208454

O=P(O)(O)O[C@H]1OC(CO)[C@@H](O)[C@H](O)C1O

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ IGF2R P11717 5/20 0.45
▸ GAA P10253 1/20 0.45
▸ TYR P14679 1/20 0.45
▸ MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7550356 1.00 L3MBTL1 (0.46) L3MBTL1IGF2RGAATYRMAPT
SCHEMBL104855 1.00 L3MBTL1 (0.46) L3MBTL1IGF2RGAATYRMAPT
SCHEMBL7549080 1.00 L3MBTL1 (0.46) L3MBTL1IGF2RGAATYRMAPT
SCHEMBL284741 1.00 L3MBTL1 (0.46) L3MBTL1IGF2RGAATYRMAPT
SCHEMBL1521155 1.00 L3MBTL1 (0.46) L3MBTL1IGF2RGAATYRMAPT
SCHEMBL24021536 1.00 L3MBTL1 (0.46) L3MBTL1IGF2RGAATYRMAPT
SCHEMBL1521609 1.00 L3MBTL1 (0.46) L3MBTL1IGF2RGAATYRMAPT
SCHEMBL7549072 1.00 L3MBTL1 (0.46) L3MBTL1IGF2RGAATYRMAPT
SCHEMBL7545194 1.00 L3MBTL1 (0.46) L3MBTL1IGF2RGAATYRMAPT
SCHEMBL1521156 1.00 L3MBTL1 (0.46) L3MBTL1IGF2RGAATYRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170204444-A9 CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-07-20 — — US disclosed
US-20170204444-A9 CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-07-20 — — US disclosed
US-20170016040-A1 CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-01-19 — — US disclosed
US-20170016040-A1 CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-01-19 — — US disclosed
US-20160161490-A1 REAGENT FOR MEASURING ENDOTOXIN AND METHOD FOR MEASURING ENDOTOXIN SAWAI PHARMACEUTICAL CO., LTD. (JP) 2016-06-09 — — US disclosed
US-9290530-B2 Chemoenzymatic synthesis of heparin and heparan sulfate analogs THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-03-22 — — US disclosed
US-9290530-B2 Chemoenzymatic synthesis of heparin and heparan sulfate analogs THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-03-22 — — US disclosed
US-20140235575-A1 CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-08-21 — — US disclosed
US-20140235575-A1 CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-08-21 — — US disclosed
US-8575131-B2 Glucuronic acid-containing glucan, process for production of same, and use of same NATIONAL UNIVERSITY CORPORATION KAGOSHIMA UNIVERSITY (JP) 2013-11-05 — — US disclosed
US-20130004979-A1 GLYCOSYLTRANSFERASE REVERSIBILITY FOR SUGAR NUCLEOTIDE SYNTHESIS AND MICROSCALE SCANNING WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-01-03 — — US disclosed
US-20120135063-A1 GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME EZAKI GLICO CO., LTD. (JP) 2012-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235575-A1 CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS HPSE, ENGASE, GALE L3MBTL1 4655/4885IGF2R 131/4885GAA 82/4885
US-20120135063-A1 GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME ENGASE, FUCA1, ALG8 L3MBTL1 4214/4885IGF2R 130/4885GAA 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback