Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 2/20 | 0.35 |
| ▸ | CLK2 | P49760 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.35 |
| ▸ | CLK3 | P49761 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038865 | 0.94 | HASPIN (0.38) | MAPTALDH1A1CLK1CRHBPHTT | |
| SCHEMBL9041045 | 0.87 | CLK1 (0.42) | MAPTALDH1A1CLK1CLK2CDK5 | |
| SCHEMBL9077636 | 0.83 | CDK2 (0.47) | MAPTALDH1A1EIF4A1CDK2PTPN1 | |
| SCHEMBL9077610 | 0.81 | ALDH1A1 (0.44) | MAPTALDH1A1EIF4A1CDK2PTPN1 | |
| SCHEMBL9219060 | 0.80 | KDM4E (0.45) | MAPTALDH1A1EIF4A1PTPN1HTT | |
| SCHEMBL9078240 | 0.78 | KDM4E (0.50) | MAPTALDH1A1PTPN1HTTTDP1 | |
| SCHEMBL9039039 | 0.77 | KMT2A (0.41) | MAPTALDH1A1HTTTDP1MEN1 | |
| SCHEMBL9078669 | 0.76 | MAPT (0.40) | MAPTALDH1A1EIF4A1CDK2PTPN1 | |
| SCHEMBL9077993 | 0.76 | KDM4E (0.49) | MAPTALDH1A1HTTTDP1KDR | |
| SCHEMBL9215091 | 0.75 | CDK2 (0.53) | MAPTALDH1A1EIF4A1CDK2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000490-A1 | BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-01-05 | — | — | WO | disclosed |