Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3550531 | 0.81 | HPGD (0.56) | HPGDALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL68410 | 0.80 | SMN1; SMN2 (0.71) | HPGDALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL7291618 | 0.75 | ALDH1A1 (0.47) | HPGDALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL7258078 | 0.75 | HPGD (0.83) | HPGDALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL7252897 | 0.75 | HPGD (0.83) | HPGDALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL9898080 | 0.72 | HPGD (0.69) | HPGDALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL7005884 | 0.72 | ALDH1A1 (0.50) | HPGDALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL17928538 | 0.72 | MAPK1 (0.46) | HPGDALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL7299832 | 0.72 | NPSR1 (0.49) | ALDH1A1SMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL11652842 | 0.71 | HPGD (0.72) | HPGDALDH1A1MAPK1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390739-B1 | Substituted aminopyrroles as stabilisers in chlorinated polymers | CIBA GEIGY AG (CH) | 1995-08-09 | — | — | EP | claimed |