Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214286 | 0.87 | NR1I2 (0.54) | NR1I2TP53ALDH1A1TDP1CYP3A4 | |
| Dimethachlor SCHEMBL67002 | 0.87 | TP53 (0.53) | NR1I2TP53ALDH1A1TDP1CYP3A4 | |
| Dimethachlor SCHEMBL8540169 | 0.87 | TP53 (0.53) | NR1I2TP53ALDH1A1TDP1CYP3A4 | |
| SCHEMBL11599043 | 0.85 | NR1I2 (0.43) | NR1I2TP53ALDH1A1TDP1CYP3A4 | |
| SCHEMBL9212997 | 0.83 | TP53 (0.50) | NR1I2TP53ALDH1A1TDP1CYP3A4 | |
| Dimethachlor SCHEMBL22534179 | 0.83 | NR1I2 (0.56) | NR1I2TP53ALDH1A1TDP1CYP3A4 | |
| SCHEMBL9208363 | 0.82 | TP53 (0.49) | NR1I2TP53ALDH1A1TDP1CYP3A4 | |
| SCHEMBL11876794 | 0.81 | ALDH1A1 (0.46) | NR1I2TP53ALDH1A1TDP1CYP3A4 | |
| SCHEMBL9210625 | 0.81 | TP53 (0.68) | NR1I2TP53ALDH1A1TDP1CYP3A4 | |
| SCHEMBL10667257 | 0.80 | TP53 (0.45) | NR1I2TP53ALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434341-B1 | Diazine derivatives | ZENECA LTD (GB) | 1995-05-17 | — | — | EP | claimed |
| EP-0357557-A2 | Synergistic mixture | CIBA-GEIGY AG (CH) | 1990-03-07 | — | — | EP | claimed |
| EP-0236268-A1 | Plant protection by means of N-halogenoacetyl isoquinolines against herbicidal halogen acetanilides | CIBA-GEIGY AG (CH) | 1987-09-09 | — | — | EP | claimed |
| EP-0378508-B1 | Antidotes to modify the resistance of cultivated plants to agrochemical agents | CIBA GEIGY AG (CH) | 1995-03-01 | — | — | EP | disclosed |
| US-5175289-A | Antidotes for protecting cultivated plants from the phytotoxic action of herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| US-5041157-A | Protecting soybeans or cereals | CIBA-GEIGY CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0378508-A2 | Antidotes to modify the resistance of cultivated plants to agrochemical agents | CIBA-GEIGY AG (CH) | 1990-07-18 | — | — | EP | disclosed |
| EP-0357557-A2 | Synergistic mixture | CIBA-GEIGY AG (CH) | 1990-03-07 | — | — | EP | disclosed |
| US-4897109-A | ACYLAMINE DERIVATIVE | CIBA-GEIGY CORPORATION (US) | 1990-01-30 | — | — | US | disclosed |
| EP-0236268-A1 | Plant protection by means of N-halogenoacetyl isoquinolines against herbicidal halogen acetanilides | CIBA-GEIGY AG (CH) | 1987-09-09 | — | — | EP | disclosed |
| US-4070179-A | Plant growth regulation with N-(2-alkoxy-ethyl)-N-chloroacetyl-2,3,6-trimethyl-anilines | CIBA-GEIGY CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |