Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094949 | 0.98 | SHBG (0.52) | SHBGEPHX1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL7761672 | 0.98 | SHBG (0.52) | SHBGEPHX1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL22803237 | 0.90 | — | — | |
| SCHEMBL29016515 | 0.90 | SHBG (0.46) | SHBGEPHX1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL23522672 | 0.87 | SHBG (0.50) | SHBGEPHX1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL9207753 | 0.86 | SHBG (0.44) | SHBGSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL9204725 | 0.84 | SHBG (0.48) | SHBGEPHX1ALDH1A1CYP1A2 | |
| SCHEMBL2997497 | 0.84 | SHBG (0.43) | SHBGEPHX1CYP1A2 | |
| SCHEMBL2342491 | 0.84 | SHBG (0.57) | SHBGEPHX1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL21350187 | 0.83 | SHBG (0.34) | SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3228272-A1 | ABLATION SYSTEM | Neuwave Medical, Inc. (US) | 2017-10-11 | — | — | EP | disclosed |
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |