Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 7/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215721 | 0.98 | KDM2B (0.41) | KDM2BMAOBMAOAMEN1KMT2A | |
| SCHEMBL9207330 | 0.97 | KDM2B (0.41) | KDM2BMAOBMAOAMEN1KMT2A | |
| Bromide SCHEMBL9206535 | 0.94 | KDM2B (0.39) | KDM2BADRA1BACHE | |
| SCHEMBL9204619 | 0.92 | KDM2B (0.42) | KDM2BMAOBMAOAMEN1KMT2A | |
| SCHEMBL9215919 | 0.92 | KDM2B (0.41) | KDM2BMAOBMAOAADRA1BHTT | |
| Hydrochloric Acid SCHEMBL9740149 | 0.92 | KDM2B (0.41) | KDM2BMAOBMAOAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9215495 | 0.90 | KDM2B (0.41) | KDM2BMAOBMAOAMEN1KMT2A | |
| SCHEMBL9208847 | 0.89 | SMPD1 (0.42) | MAOBMAOAMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL9206857 | 0.89 | CYP3A4 (0.43) | MAOBMAOAMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL9214727 | 0.88 | KDM2B (0.39) | KDM2BMAOBMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |