Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204619 | 0.99 | KDM2B (0.42) | KDM2BADRA1BMAOAMAOBACHE | |
| Hydrochloric Acid SCHEMBL9740149 | 0.98 | KDM2B (0.41) | KDM2BADRA1BMAOAMAOBABCB1 | |
| SCHEMBL9207330 | 0.95 | KDM2B (0.41) | KDM2BADRA1BMAOAMAOBACHE | |
| SCHEMBL9215721 | 0.94 | KDM2B (0.41) | KDM2BADRA1BMAOAMAOBABCB1 | |
| SCHEMBL9209353 | 0.92 | KDM2B (0.44) | KDM2BADRA1BMAOAMAOBACHE | |
| SCHEMBL9212391 | 0.91 | KDM2B (0.39) | KDM2BMAOAMAOBACHE | |
| Hydrochloric Acid SCHEMBL9214727 | 0.90 | KDM2B (0.39) | KDM2BMAOAMAOB | |
| Hydrochloric Acid SCHEMBL9211982 | 0.89 | KDM2B (0.44) | KDM2BMAOAMAOB | |
| SCHEMBL9214059 | 0.89 | ADRA1B (0.42) | ADRA1BACHEABCB1 | |
| SCHEMBL9213423 | 0.88 | ADRA1B (0.42) | ADRA1BACHEABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |