Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209632 | 1.00 | AGTR1 (0.56) | AGTR1 | |
| SCHEMBL7432923 | 0.93 | AGTR1 (0.60) | AGTR1 | |
| SCHEMBL7432919 | 0.93 | AGTR1 (0.60) | AGTR1 | |
| SCHEMBL9211331 | 0.92 | — | — | |
| SCHEMBL9211338 | 0.92 | — | — | |
| SCHEMBL8957178 | 0.89 | AGTR1 (0.56) | AGTR1 | |
| SCHEMBL8957181 | 0.89 | AGTR1 (0.56) | AGTR1 | |
| SCHEMBL9205035 | 0.88 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL9205029 | 0.88 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL9204638 | 0.87 | AGTR1 (0.52) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427463-B1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORP (US) | 1995-03-08 | — | — | EP | claimed |
| EP-0427463-A1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-15 | — | — | EP | claimed |
| EP-0427463-B1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORP (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0427463-A1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-15 | — | — | EP | disclosed |