Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9209072 | 0.93 | HTR2A (0.41) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| Fumaric Acid SCHEMBL9209066 | 0.93 | HTR2A (0.41) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| SCHEMBL9209645 | 0.90 | HTR2A (0.52) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL9212821 | 0.89 | HTR2A (0.51) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL9213650 | 0.89 | HTR2A (0.51) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL9212810 | 0.89 | HTR2A (0.51) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL9211654 | 0.85 | HTR2A (0.47) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| SCHEMBL9214026 | 0.81 | KDM4E (0.52) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL9218819 | 0.81 | KDM4E (0.51) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL9211945 | 0.76 | HTR2A (0.51) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411912-B1 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | SANKYO CO (JP) | 1995-04-19 | — | — | EP | disclosed |