Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211000 | 0.94 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9209621 | 0.94 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9201015 | 0.93 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9200394 | 0.93 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9210420 | 0.93 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9274772 | 0.92 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9208579 | 0.91 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL9276761 | 0.91 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9203154 | 0.91 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9206086 | 0.90 | AGTR1 (0.60) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664803-A1 | N-ARYLHETEROARYLALKYL 1-CYCLOALKYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994008989-A1 | N-ARYLHETEROARYLALKYL 1-CYCLOALKYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1994-04-28 | — | — | WO | disclosed |