Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013949 | 0.80 | CHEK1 (0.50) | ASAH1ELANESLC22A12KMOCHEK1 | |
| SCHEMBL5120623 | 0.79 | HSD17B10 (0.56) | HSD17B10POLBTSHRKDM4EALDH1A1 | |
| SCHEMBL2466233 | 0.77 | CHEK1 (0.36) | ASAH1ELANESLC22A12KMOCHEK1 | |
| Hydrochloric Acid SCHEMBL2925512 | 0.76 | CHEK1 (0.36) | ASAH1ELANESLC22A12KMOCHEK1 | |
| Hydrochloric Acid SCHEMBL3871255 | 0.76 | CHEK1 (0.36) | ASAH1ELANESLC22A12KMOCHEK1 | |
| Bromide SCHEMBL2933641 | 0.76 | CHEK1 (0.36) | ASAH1ELANESLC22A12KMOCHEK1 | |
| Bromide SCHEMBL2931155 | 0.76 | CHEK1 (0.36) | ASAH1ELANESLC22A12KMOCHEK1 | |
| SCHEMBL4769167 | 0.74 | ELANE (0.44) | HSD17B10POLBTSHRMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL5049276 | 0.72 | TSHR (0.38) | HSD17B10POLBTSHRKDM4EALDH1A1 | |
| SCHEMBL30457321 | 0.71 | CHEK1 (0.67) | HSD17B10POLBTSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544218-B1 | Arylindazole derivatives and their use | SUMITOMO CHEMICAL CO (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5266556-A | Herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-30 | — | — | US | disclosed |
| EP-0544218-A1 | Arylindazole derivatives and their use | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-06-02 | — | — | EP | disclosed |