Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.42 |
| ▸ | HMGCR | P04035 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213040 | 1.00 | PTPN7 (0.42) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL9210902 | 1.00 | PTPN7 (0.42) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL9212952 | 0.98 | PTPN7 (0.39) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL9211881 | 0.95 | PTPN7 (0.47) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL9214612 | 0.95 | PTPN7 (0.47) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL9213118 | 0.95 | PTPN7 (0.47) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL9207539 | 0.95 | PTPN7 (0.47) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL9213487 | 0.89 | RECQL (0.52) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL9208114 | 0.86 | RAB9A (0.36) | PTPN7HMGCRRECQLTDP1RAB9A | |
| SCHEMBL2119404 | 0.85 | TSHR (0.38) | PTPN7HMGCRRECQLTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |